A Review of Early Detection of Lung Diseases based on Deep Learning Models
DOI:
https://doi.org/10.65542/djei.v2i1.21Keywords:
Lung Diseases, Pneumonia, CNN, Deep Learning, X-ray, Ensemble LearningAbstract
Earlier diagnosis of pulmonary disease is greatly significant in enhancing treatment impacts and lowering systems' medical workload. As increasingly more cases of pulmonary disease accumulate, methods of deep learning (DL) have increasingly become a viable option towards assisting physicians with diagnoses, particularly through the interpretation of chest X-ray (CXR) images. This paper presents the latest DL-based models and methods for early detection of lung diseases and evaluates their performance and accuracy of disease classification. It also demonstrates the power of ensemble learning methods, a combination of ResNet, EfficientNet, and Inception models, for enhancing the accuracy and reliability of diagnosis systems, especially in handling complicated patterns of diseases. The study seeks to introduce newer directions for research and explore the direction towards intelligent and scalable diagnosis solutions that can potentially make a critical contribution towards enhanced early detection and improving the quality of patient care.
References
M. Chalie and Z. Mossie, “Pulmonary Disease Identification and Classification Using Deep Learning Approach,” EIJET, vol. 1, no. 2, pp. 50–65, Dec. 2023, doi: 10.59122/144CFC16.
Poloju, N., & Rajaram, A. (2025). Hybrid technique for lung disease classification based on machine learning and optimization using X-ray images. Multimedia Tools and Applications, 84(21), 23531-23553.
Y. Liang, X. Liu, H. Xia, Y. Cang, Z. Zheng, and Y. Yang, “Convolutional Neural Networks for Predictive Modeling of Lung Disease,” in 2024 IEEE 6th International Conference on Power, Intelligent Computing and Systems (ICPICS), Shenyang, China: IEEE, Jul. 2024, pp. 803–808. doi: 10.1109/ICPICS62053.2024.10796475.
A. Bhandary et al., “Deep-learning framework to detect lung abnormality – A study with chest X-Ray and lung CT scan images,” Pattern Recognition Letters, vol. 129, pp. 271–278, Jan. 2020, doi: 10.1016/j.patrec.2019.11.013.
R. Ramalingam and V. Chinnaiyan, “A comparative analysis of chronic obstructive pulmonary disease using machine learning, and deep learning,” IJECE, vol. 13, no. 1, p. 389, Feb. 2023, doi: 10.11591/ijece.v13i1.pp389-399.
J. Dhar, “Multistage Ensemble Learning Model With Weighted Voting and Genetic Algorithm Optimization Strategy for Detecting Chronic Obstructive Pulmonary Disease,” IEEE Access, vol. 9, pp. 48640–48657, 2021, doi: 10.1109/ACCESS.2021.3067949.
A. Ait Nasser and M. A. Akhloufi, “A Review of Recent Advances in Deep Learning Models for Chest Disease Detection Using Radiography,” Diagnostics, vol. 13, no. 1, p. 159, Jan. 2023, doi: 10.3390/diagnostics13010159.
S. Vidyasri and S. Saravanan, “Enhanced deep transfer learning with multi-feature fusion for lung disease detection,” Multimed Tools Appl, vol. 83, no. 19, pp. 56321–56345, Dec. 2023, doi: 10.1007/s11042-023-17767-8.
K. Sriporn, C.-F. Tsai, C.-E. Tsai, and P. Wang, “Analyzing Lung Disease Using Highly Effective Deep Learning Techniques,” Healthcare, vol. 8, no. 2, p. 107, Apr. 2020, doi: 10.3390/healthcare8020107.
P. M. Shakeel, M. A. Burhanuddin, and M. I. Desa, “Lung cancer detection from CT image using improved profuse clustering and deep learning instantaneously trained neural networks,” Measurement, vol. 145, pp. 702–712, Oct. 2019, doi: 10.1016/j.measurement.2019.05.027.
“Multiple Lung Diseases Classification from Chest X- Ray Images using Deep Learning approach,” IJATCSE, vol. 10, no. 5, pp. 2936–2946, Oct. 2021, doi: 10.30534/ijatcse/2021/021052021.
Mohammad Shafiquzzaman Bhuiyan et al., “Advancements in Early Detection of Lung Cancer in Public Health: A Comprehensive Study Utilizing Machine Learning Algorithms and Predictive Models,” JCSTS, vol. 6, no. 1, pp. 113–121, Jan. 2024, doi: 10.32996/jcsts.2024.6.1.12.
S. A. Shehab, K. K. Mohammed, A. Darwish, and A. E. Hassanien, “Deep learning and feature fusion-based lung sound recognition model to diagnoses the respiratory diseases,” Soft Comput, vol. 28, no. 19, pp. 11667–11683, Oct. 2024, doi: 10.1007/s00500-024-09866-x.
T. H. Kim, M. Krichen, S. Ojo, M. A. Alamro, and G. A. Sampedro, “TSSG-CNN: A Tuberculosis Semantic Segmentation-Guided Model for Detecting and Diagnosis Using the Adaptive Convolutional Neural Network,” Diagnostics, vol. 14, no. 11, p. 1174, Jun. 2024, doi: 10.3390/diagnostics14111174.
S. Kumar, H. Kumar, G. Kumar, S. P. Singh, A. Bijalwan, and M. Diwakar, “A methodical exploration of imaging modalities from dataset to detection through machine learning paradigms in prominent lung disease diagnosis: a review,” BMC Med Imaging, vol. 24, no. 1, p. 30, Feb. 2024, doi: 10.1186/s12880-024-01192-w.
X. Shen and H. Liu, “Using machine learning for early detection of chronic obstructive pulmonary disease: a narrative review,” Respir Res, vol. 25, no. 1, p. 336, Sep. 2024, doi: 10.1186/s12931-024-02960-6.
M. Alotaibi et al., “Exploiting histopathological imaging for early detection of lung and colon cancer via ensemble deep learning model,” Sci Rep, vol. 14, no. 1, p. 20434, Sep. 2024, doi: 10.1038/s41598-024-71302-9.
N. Tawfik, H. M. Emara, W. El-Shafai, N. F. Soliman, A. D. Algarni, and F. E. A. El-Samie, “Enhancing Early Detection of Lung Cancer through Advanced Image Processing Techniques and Deep Learning Architectures for CT Scans,” CMC, vol. 81, no. 1, pp. 271–307, 2024, doi: 10.32604/cmc.2024.052404.
S. T. Ahmed and S. M. Kadhem, “Alzheimer’s disease prediction using three machine learning methods,” IJEECS, vol. 27, no. 3, p. 1689, Sep. 2022, doi: 10.11591/ijeecs.v27.i3.pp1689-1697.
Z. Zhu et al., “Development and application of a deep learning-based comprehensive early diagnostic model for chronic obstructive pulmonary disease,” Respir Res, vol. 25, no. 1, p. 167, Apr. 2024, doi: 10.1186/s12931-024-02793-3.
R. Karla and R. Yalavarthi, “A Hybrid RNN-based Deep Learning Model for Lung Cancer and COPD Detection,” Eng. Technol. Appl. Sci. Res., vol. 14, no. 5, pp. 16847–16853, Oct. 2024, doi: 10.48084/etasr.8181.
M. Irtaza, A. Ali, M. Gulzar, and A. Wali, “Multi-Label Classification of Lung Diseases Using Deep Learning,” IEEE Access, vol. 12, pp. 124062–124080, 2024, doi: 10.1109/ACCESS.2024.3454537.
S. Kumar et al., “A novel multimodal framework for early diagnosis and classification of COPD based on CT scan images and multivariate pulmonary respiratory diseases,” Computer Methods and Programs in Biomedicine, vol. 243, p. 107911, Jan. 2024, doi: 10.1016/j.cmpb.2023.107911.
M. H. Al-Sheikh, O. Al Dandan, A. S. Al-Shamayleh, H. A. Jalab, and R. W. Ibrahim, “Multi-class deep learning architecture for classifying lung diseases from chest X-Ray and CT images,” Sci Rep, vol. 13, no. 1, p. 19373, Nov. 2023, doi: 10.1038/s41598-023-46147-3.
M. A. Shames and M. Y. Kamil, “Early Diagnosis of Lung Infection via Deep Learning Approach,” Int. Res. J. multidiscip. Technovation, pp. 216–224, May 2024, doi: 10.54392/irjmt24316.
S. A. Hasanah, A. A. Pravitasari, A. S. Abdullah, I. N. Yulita, and M. H. Asnawi, “A Deep Learning Review of ResNet Architecture for Lung Disease Identification in CXR Image,” Applied Sciences, vol. 13, no. 24, p. 13111, Dec. 2023, doi: 10.3390/app132413111.
R. R. Irshad et al., “A Novel IoT-Enabled Healthcare Monitoring Framework and Improved Grey Wolf Optimization Algorithm-Based Deep Convolution Neural Network Model for Early Diagnosis of Lung Cancer,” Sensors, vol. 23, no. 6, p. 2932, Mar. 2023, doi: 10.3390/s23062932.
A. M. Alqudah, S. Qazan, and Y. M. Obeidat, “Deep learning models for detecting respiratory pathologies from raw lung auscultation sounds,” Soft Comput, vol. 26, no. 24, pp. 13405–13429, Dec. 2022, doi: 10.1007/s00500-022-07499-6.
F. Hussein et al., “Hybrid CLAHE-CNN Deep Neural Networks for Classifying Lung Diseases from X-ray Acquisitions,” Electronics, vol. 11, no. 19, p. 3075, Sep. 2022, doi: 10.3390/electronics11193075.
A. T. Abdulahi, R. O. Ogundokun, A. R. Adenike, M. A. Shah, and Y. K. Ahmed, “PulmoNet: a novel deep learning based pulmonary diseases detection model,” BMC Med Imaging, vol. 24, no. 1, p. 51, Feb. 2024, doi: 10.1186/s12880-024-01227-2.
S. R. Vinta, B. Lakshmi, M. A. Safali, and G. S. C. Kumar, “Segmentation and Classification of Interstitial Lung Diseases Based on Hybrid Deep Learning Network Model,” IEEE Access, vol. 12, pp. 50444–50458, 2024, doi: 10.1109/ACCESS.2024.3383144.
S. S.K.B et al., “An enhanced multimodal fusion deep learning neural network for lung cancer classification,” Systems and Soft Computing, vol. 6, p. 200068, Dec. 2024, doi: 10.1016/j.sasc.2023.200068.
S. Wankhade and V. S., “A novel hybrid deep learning method for early detection of lung cancer using neural networks,” Healthcare Analytics, vol. 3, p. 100195, Nov. 2023, doi: 10.1016/j.health.2023.100195.
Y. Akbulut, “Automated Pneumonia Based Lung Diseases Classification with Robust Technique Based on a Customized Deep Learning Approach,” Diagnostics, vol. 13, no. 2, p. 260, Jan. 2023, doi: 10.3390/diagnostics13020260.
H. A. Khater and S. A. Gamel, “Early diagnosis of respiratory system diseases (RSD) using deep convolutional neural networks,” J Ambient Intell Human Comput, vol. 14, no. 9, pp. 12273–12283, Sep. 2023, doi: 10.1007/s12652-023-04659-w.
M. Jasmine Pemeena Priyadarsini et al., “Lung Diseases Detection Using Various Deep Learning Algorithms,” Journal of Healthcare Engineering, vol. 2023, no. 1, p. 3563696, Jan. 2023, doi: 10.1155/2023/3563696.
G. S. Nandeesh, M. Nagabushanam, S. Pramodkumar, and S. Nandini, “Lung parenchyma segmentation and nodule detection using deep learning,” J Opt, vol. 53, no. 1, pp. 635–642, Feb. 2024, doi: 10.1007/s12596-023-01187-w.
J. Weiss et al., “Deep learning to estimate lung disease mortality from chest radiographs,” Nat Commun, vol. 14, no. 1, p. 2797, May 2023, doi: 10.1038/s41467-023-37758-5.
Y. Hussain Ali et al., “Multi-Layered Non-Local Bayes Model for Lung Cancer Early Diagnosis Prediction with the Internet of Medical Things,” Bioengineering, vol. 10, no. 2, p. 138, Jan. 2023, doi: 10.3390/bioengineering10020138.
D. Srivastava et al., “Early Detection of Lung Nodules Using a Revolutionized Deep Learning Model,” Diagnostics, vol. 13, no. 22, p. 3485, Nov. 2023, doi: 10.3390/diagnostics13223485.
R. Mothkur and B. N. Veerappa, “Classification Of Lung Cancer Using Lightweight Deep Neural Networks,” Procedia Computer Science, vol. 218, pp. 1869–1877, 2023, doi: 10.1016/j.procs.2023.01.164.
A. A. Shah, H. A. M. Malik, A. Muhammad, A. Alourani, and Z. A. Butt, “Deep learning ensemble 2D CNN approach towards the detection of lung cancer,” Sci Rep, vol. 13, no. 1, p. 2987, Feb. 2023, doi: 10.1038/s41598-023-29656-z.
J. Arun Prakash, C. Asswin, V. Ravi, V. Sowmya, and K. Soman, “Pediatric pneumonia diagnosis using stacked ensemble learning on multi-model deep CNN architectures,” Multimed Tools Appl, vol. 82, no. 14, pp. 21311–21351, Jun. 2023, doi: 10.1007/s11042-022-13844-6.
Y. H. Bhosale and K. S. Patnaik, “PulDi-COVID: Chronic obstructive pulmonary (lung) diseases with COVID-19 classification using ensemble deep convolutional neural network from chest X-ray images to minimize severity and mortality rates,” Biomedical Signal Processing and Control, vol. 81, p. 104445, Mar. 2023, doi: 10.1016/j.bspc.2022.104445.
“ELREI: Ensemble Learning of ResNet, EfficientNet, and Inception-v3 for Lung Disease Classification based on Chest X-Ray Image,” IJIES, vol. 16, no. 5, pp. 149–161, Oct. 2023, doi: 10.22266/ijies2023.1031.14.
S. Gite, A. Mishra, and K. Kotecha, “Enhanced lung image segmentation using deep learning,” Neural Comput & Applic, vol. 35, no. 31, pp. 22839–22853, Nov. 2023, doi: 10.1007/s00521-021-06719-8.
V. Ravi, V. Acharya, and M. Alazab, “A multichannel EfficientNet deep learning-based stacking ensemble approach for lung disease detection using chest X-ray images,” Cluster Comput, vol. 26, no. 2, pp. 1181–1203, Apr. 2023, doi: 10.1007/s10586-022-03664-6.
G. M. M. Alshmrani, Q. Ni, R. Jiang, H. Pervaiz, and N. M. Elshennawy, “A deep learning architecture for multi-class lung diseases classification using chest X-ray (CXR) images,” Alexandria Engineering Journal, vol. 64, pp. 923–935, Feb. 2023, doi: 10.1016/j.aej.2022.10.053.
H. Nishikiori et al., “Deep-learning algorithm to detect fibrosing interstitial lung disease on chest radiographs,” Eur Respir J, vol. 61, no. 2, p. 2102269, Feb. 2023, doi: 10.1183/13993003.02269-2021.
A. Das, “Adaptive UNet-based Lung Segmentation and Ensemble Learning with CNN-based Deep Features for Automated COVID-19 Diagnosis,” Multimed Tools Appl, vol. 81, no. 4, pp. 5407–5441, Feb. 2022, doi: 10.1007/s11042-021-11787-y.
A. Kabiraj, T. Meena, P. B. Reddy, and S. Roy, “Detection and Classification of Lung Disease Using Deep Learning Architecture from X-ray Images,” in Advances in Visual Computing, vol. 13598, G. Bebis, B. Li, A. Yao, Y. Liu, Y. Duan, M. Lau, R. Khadka, A. Crisan, and R. Chang, Eds., in Lecture Notes in Computer Science, vol. 13598. , Cham: Springer International Publishing, 2022, pp. 444–455. doi: 10.1007/978-3-031-20713-6_34.
S. Goyal and R. Singh, “Detection and classification of lung diseases for pneumonia and Covid-19 using machine and deep learning techniques,” J Ambient Intell Human Comput, vol. 14, no. 4, pp. 3239–3259, Apr. 2023, doi: 10.1007/s12652-021-03464-7.
R. H, T. Kumaravel, P. Natesan, B. B M, S. Sangeetha, and S. Dharanesh, “Comparative Study of Deep Learning Techniques for Automated Classification of Lung Diseases,” in 2023 4th International Conference on Smart Electronics and Communication (ICOSEC), Trichy, India: IEEE, Sep. 2023, pp. 1324–1328. doi: 10.1109/ICOSEC58147.2023.10276053.
A. Bhattacharjee et al., “A multi-class deep learning model for early lung cancer and chronic kidney disease detection using computed tomography images,” Front. Oncol., vol. 13, p. 1193746, Jun. 2023, doi: 10.3389/fonc.2023.1193746.
H. I. Hussein, A. O. Mohammed, M. M. Hassan, and R. J. Mstafa, “Lightweight deep CNN-based models for early detection of COVID-19 patients from chest X-ray images,” Expert Systems with Applications, vol. 223, p. 119900, Aug. 2023, doi: 10.1016/j.eswa.2023.119900.
Md. Nahiduzzaman et al., “Detection of various lung diseases including COVID-19 using extreme learning machine algorithm based on the features extracted from a lightweight CNN architecture,” Biocybernetics and Biomedical Engineering, vol. 43, no. 3, pp. 528–550, Jul. 2023, doi: 10.1016/j.bbe.2023.06.003.
N. S. Reddy and V. Khanaa, “Diagnosing and categorizing of pulmonary diseases using Deep learning conventional Neural network,” IJERR, vol. 31, no. Spl Volume, pp. 12–22, Jul. 2023, doi: 10.52756/10.52756/ijerr.2023.v31spl.002.
S. Ashwini, J. R. Arunkumar, R. T. Prabu, N. H. Singh, and N. P. Singh, “Diagnosis and multi-classification of lung diseases in CXR images using optimized deep convolutional neural network,” Soft Comput, vol. 28, no. 7–8, pp. 6219–6233, Apr. 2024, doi: 10.1007/s00500-023-09480-3.
S. Bharati, P. Podder, and M. R. H. Mondal, “Hybrid deep learning for detecting lung diseases from X-ray images,” Informatics in Medicine Unlocked, vol. 20, p. 100391, 2020, doi: 10.1016/j.imu.2020.100391.
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