Green Synthesis of Metal Oxide Nanoparticles Using Plant Extracts with Emphasis on Vigna unguiculata (Cowpea): A Review

Authors

  • Lawand L. Mustafa Department of Petroleum Geology, Duhok Polytechnic University
  • Amin K. Qasim Department of Chemistry, University of Zakho https://orcid.org/0000-0003-2354-9867

DOI:

https://doi.org/10.65542/djei.v2i1.24

Keywords:

Metal Oxide 2, Green Synthesis 3, Cowpea Seed 4, Nanoscale and 5, Eco-Friendly NPs

Abstract

The green synthesis of metal oxide nanoparticles is received increasing attention due to its offer more environmentally safe alternative compared to conventional chemical methods, with many promising applications. This review focuses on usage of Vigna unguiculata (cowpea) in biosynthesis of metal oxide nanoparticles by showing its role as sustainable and low-cost reducing and stabilizing agent. The synthesis procedure is described, with emphasis on function of plant phytochemicals which help in the formation of nanoparticles. Different characterization methods are discussed, like field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), and UV–Vis spectroscopy, to identify structure, morphology, and chemical nature of the nanoparticles. The review also considers the challenges associated with scaling up green synthesis processes and suggests future research directions to improve practical applications. By addressing these aspects, this review aims to provide a better understanding of the synthesis mechanisms, key properties, and real-world applications of metal oxide nanoparticles produced using Vigna unguiculata, thereby supporting the growing field of green nanotechnology.

References

Harish, K.K.; Nagasamy, V.; Himangshu, B.; Anuttam, K. Metallic Nanoparticle: A Review. Biomed J Sci &Tech Res 2018, 4, doi:10.26717/BJSTR.2018.04.001011. DOI: https://doi.org/10.26717/BJSTR.2018.04.0001011

Jeevanandam, J.; Barhoum, A.; Chan, Y.S.; Dufresne, A.; Danquah, M.K. Review on Nanoparticles and Nanostructured Materials: History, Sources, Toxicity and Regulations. Beilstein Journal of Nanotechnology 2018, 9, 1050–1074, doi:10.3762/bjnano.9.98. DOI: https://doi.org/10.3762/bjnano.9.98

Kumar, R.; Pulikanti, G.R.; Shankar, K.R.; Rambabu, D.; Mangili, V.; Kumbam, L.R.; Sagara, P.S.; Nakka, N.; Yogesh, M. Surface Coating and Functionalization of Metal and Metal Oxide Nanoparticles for Biomedical Applications. In Metal Oxides for Biomedical and Biosensor Applications; Elsevier, 2022; pp. 205–231. DOI: https://doi.org/10.1016/B978-0-12-823033-6.00007-7

Dawodu, F.A.; Onuh, C.U.; Akpomie, K.G.; Unuabonah, E.I. Synthesis of Silver Nanoparticle from Vigna Unguiculata Stem as Adsorbent for Malachite Green in a Batch System. SN Appl. Sci. 2019, 1, 346, doi:10.1007/s42452-019-0353-3.

Chavali, M.S.; Nikolova, M.P. Metal Oxide Nanoparticles and Their Applications in Nanotechnology. SN Appl. Sci. 2019, 1, 607, doi:10.1007/s42452-019-0592-3. DOI: https://doi.org/10.1007/s42452-019-0592-3

Deline, A.R.; Nason, J.A. Evaluation of Labeling Methods Used for Investigating the Environmental Behavior and Toxicity of Metal Oxide Nanoparticles. Environ. Sci. Nano 2019, 6, 1043–1066, doi:10.1039/C8EN01187G. DOI: https://doi.org/10.1039/C8EN01187G

Chen, X.; Liu, L.; Yu, P.Y.; Mao, S.S. Increasing Solar Absorption for Photocatalysis with Black Hydrogenated Titanium Dioxide Nanocrystals. Science (1979). 2011, 331, 746–750, doi:10.1126/science.1200448. DOI: https://doi.org/10.1126/science.1200448

Garcia, G.; Buonsanti, R.; Runnerstrom, E.L.; Mendelsberg, R.J.; Llordes, A.; Anders, A.; Richardson, T.J.; Milliron, D.J. Dynamically Modulating the Surface Plasmon Resonance of Doped Semiconductor Nanocrystals. Nano Lett. 2011, 11, 4415–4420, doi:10.1021/nl202597n. DOI: https://doi.org/10.1021/nl202597n

Buonsanti, R.; Milliron, D.J. Chemistry of Doped Colloidal Nanocrystals. Chemistry of Materials 2013, 25, 1305–1317, doi:10.1021/cm304104m. DOI: https://doi.org/10.1021/cm304104m

Lounis, S.D.; Runnerstrom, E.L.; Bergerud, A.; Nordlund, D.; Milliron, D.J. Influence of Dopant Distribution on the Plasmonic Properties of Indium Tin Oxide Nanocrystals. J. Am. Chem. Soc. 2014, 136, 7110–7116, doi:10.1021/ja502541z. DOI: https://doi.org/10.1021/ja502541z

Pelaez, M.; Nolan, N.T.; Pillai, S.C.; Seery, M.K.; Falaras, P.; Kontos, A.G.; Dunlop, P.S.M.; Hamilton, J.W.J.; Byrne, J.A.; O’Shea, K.; et al. A Review on the Visible Light Active Titanium Dioxide Photocatalysts for Environmental Applications. Appl. Catal. B 2012, 125, 331–349, doi:10.1016/j.apcatb.2012.05.036. DOI: https://doi.org/10.1016/j.apcatb.2012.05.036

Mustafa, L.L.; Qasim, A.K. Facile Green Synthesis of Mn Doped NiO Nanoparticles Using Vigna Unguiculata Seed for Photocatalytic Degradation of Toluidine Blue. Int. J. Environ. Anal. Chem. 2025, 105, 8902–8922, doi:10.1080/03067319.2025.2487850. DOI: https://doi.org/10.1080/03067319.2025.2487850

Bhat, S.V.; Deepak, F.L. Tuning the Bandgap of ZnO by Substitution with Mn2+, Co2+ and Ni2+. Solid State Commun. 2005, 135, 345–347, doi:10.1016/j.ssc.2005.05.051. DOI: https://doi.org/10.1016/j.ssc.2005.05.051

Lounis, S.D.; Runnerstrom, E.L.; Llordés, A.; Milliron, D.J. Defect Chemistry and Plasmon Physics of Colloidal Metal Oxide Nanocrystals. J. Phys. Chem. Lett. 2014, 5, 1564–1574, doi:10.1021/jz500440e. DOI: https://doi.org/10.1021/jz500440e

Schimpf, A.M.; Lounis, S.D.; Runnerstrom, E.L.; Milliron, D.J.; Gamelin, D.R. Redox Chemistries and Plasmon Energies of Photodoped In 2 O 3 and Sn-Doped In 2 O 3 (ITO) Nanocrystals. J. Am. Chem. Soc. 2015, 137, 518–524, doi:10.1021/ja5116953. DOI: https://doi.org/10.1021/ja5116953

Kumari, S.; Raturi, S.; Kulshrestha, S.; Chauhan, K.; Dhingra, S.; András, K.; Thu, K.; Khargotra, R.; Singh, T. A Comprehensive Review on Various Techniques Used for Synthesizing Nanoparticles. Journal of Materials Research and Technology 2023, 27, 1739–1763, doi:10.1016/j.jmrt.2023.09.291. DOI: https://doi.org/10.1016/j.jmrt.2023.09.291

Kuppusamy, P.; Yusoff, M.M.; Maniam, G.P.; Govindan, N. Biosynthesis of Metallic Nanoparticles Using Plant Derivatives and Their New Avenues in Pharmacological Applications – An Updated Report. Saudi Pharmaceutical Journal 2016, 24, 473–484, doi:10.1016/j.jsps.2014.11.013. DOI: https://doi.org/10.1016/j.jsps.2014.11.013

Chaudhary, J.; Tailor, G.; Yadav, M.; Mehta, C. Green Route Synthesis of Metallic Nanoparticles Using Various Herbal Extracts: A Review. Biocatal. Agric. Biotechnol. 2023, 50, 102692, doi:10.1016/j.bcab.2023.102692. DOI: https://doi.org/10.1016/j.bcab.2023.102692

Alshammari, B.H.; Lashin, M.M.A.; Mahmood, M.A.; Al-Mubaddel, F.S.; Ilyas, N.; Rahman, N.; Sohail, M.; Khan, A.; Abdullaev, S.S.; Khan, R. Organic and Inorganic Nanomaterials: Fabrication, Properties and Applications. RSC Adv. 2023, 13, 13735–13785, doi:10.1039/D3RA01421E. DOI: https://doi.org/10.1039/D3RA01421E

Joshi, N.; Pandey, D.K.; Mistry, B.G.; Singh, D.K. Metal Oxide Nanoparticles: Synthesis, Properties, Characterization, and Applications. In Nanomaterials; Springer Nature Singapore: Singapore, 2023; pp. 103–144. DOI: https://doi.org/10.1007/978-981-19-7963-7_5

Naikoo, G.A.; Mustaqeem, M.; Hassan, I.U.; Awan, T.; Arshad, F.; Salim, H.; Qurashi, A. Bioinspired and Green Synthesis of Nanoparticles from Plant Extracts with Antiviral and Antimicrobial Properties: A Critical Review. Journal of Saudi Chemical Society 2021, 25, 101304, doi:10.1016/j.jscs.2021.101304. DOI: https://doi.org/10.1016/j.jscs.2021.101304

Radulescu, D.-M.; Surdu, V.-A.; Ficai, A.; Ficai, D.; Grumezescu, A.-M.; Andronescu, E. Green Synthesis of Metal and Metal Oxide Nanoparticles: A Review of the Principles and Biomedical Applications. Int. J. Mol. Sci. 2023, 24, 15397, doi:10.3390/ijms242015397. DOI: https://doi.org/10.3390/ijms242015397

S., S. Pharmacological Activities of Vigna Unguiculata (L) Walp: A Review. International Journal of Pharma And Chemical Research 2017, 3, 44–49.

Zaheer, M.; Ahmed, S.; Hassan, M.M. Vigna Unguiculata (L.) Walp. (Papilionaceae): A Review of Medicinal Uses, Phytochemistry and Pharmacology. ~ 1349 ~ Journal of Pharmacognosy and Phytochemistry 2020, 9.

Chatterjee, A.; Abraham, J.; Ajantha, M.; Talekar, A.; Revathy, N. Biosynthesis, Antimicrobial and Cytotoxic Effects of Titanium Dioxide Nanoparticles Using Vigna Unguiculata Seeds. International Journal of Pharmacognosy and Phytochemical Research 2017, 9, 95–99, doi:10.25258/ijpapr.v9i1.8047. DOI: https://doi.org/10.25258/ijpapr.v9i1.8047

Mohammadi, S.; Pourseyedi, S.; Amini, A. Green Synthesis of Silver Nanoparticles with a Long Lasting Stability Using Colloidal Solution of Cowpea Seeds (Vigna Sp. L). J. Environ. Chem. Eng. 2016, 4, 2023–2032, doi:10.1016/j.jece.2016.03.026. DOI: https://doi.org/10.1016/j.jece.2016.03.026

Jose Vazhacharickal, P.; Krishna, G.S. Green Synthesis of Silver, Copper and Zinc Nanoparticles from Mung Bean (Vigna Radiata) and Cowpea (Vigna Unguiculata) Exudates and Evaluation of Their Antibacterial Activity: An O... International Journal of Current Research and Academic Review Green Synthesis of Silver, Copper and Zinc Nanoparticles from Mung Bean (Vigna Radiata) and Cowpea (Vigna Unguiculata) Exudates and Evaluation of Their Antibacterial Activity: An Overview. Int.J.Curr.Res.Aca.Rev 2022, 10, 48–81, doi:10.20546/ijcrar.2022.1006.006.

Alsukaibi, A.K.D.; Khan, S.; Ali Khan, M.W.; Rafi, Z.; Al-Otaibi, A.; Alshamari, A.K.A.A.; Kaur, K.; Mechi, L.; Alimi, F.R.; Alshammari, E.M.; et al. Eco-Synthesis of Gold Nanoparticles Using Vigna Unguiculata Seed Extract: A Leap in the Direction of Antiglycation Remedies. Sci. Adv. Mater. 2024, 16, 614–623, doi:10.1166/sam.2024.4671. DOI: https://doi.org/10.1166/sam.2024.4671

Perera BR; Kandiah M Microwave Assisted One-Pot Green Synthesis of Silver Nanoparticles Using Leaf Extracts from Vigna Unguiculate: Evaluation of Antioxidant and Antimicrobial Activities; 2018; Vol. 5;. DOI: https://doi.org/10.4038/ijms.v5i2.100

Ramdath, S.; Mellem, J.; Mbatha, L.S. Anticancer and Antimicrobial Activity Evaluation of Cowpea-Porous-Starch-Formulated Silver Nanoparticles. J. Nanotechnol. 2021, 2021, doi:10.1155/2021/5525690. DOI: https://doi.org/10.1155/2021/5525690

Aigbe, U.O.; Osibote, O.A. Green Synthesis of Metal Oxide Nanoparticles, and Their Various Applications. Journal of Hazardous Materials Advances 2024, 13, 100401, doi:10.1016/j.hazadv.2024.100401. DOI: https://doi.org/10.1016/j.hazadv.2024.100401

Mulu, M.; Tefera, M.; Guadie, A.; Basavaiah, K. Biosynthesis, Characterization and Study of the Application of Silver Nanoparticle for 4-Nitrophenol Reduction, and Antimicrobial Activities. Biotechnology Reports 2024, 42, e00838, doi:10.1016/j.btre.2024.e00838. DOI: https://doi.org/10.1016/j.btre.2024.e00838

Dawodu, F.A.; Onuh, C.U.; Akpomie, K.G.; Unuabonah, E.I. Synthesis of Silver Nanoparticle from Vigna Unguiculata Stem as Adsorbent for Malachite Green in a Batch System. SN Appl. Sci. 2019, 1, doi:10.1007/s42452-019-0353-3. DOI: https://doi.org/10.1007/s42452-019-0353-3

Hussain, A.; Ali, S.; Rizwan, M.; Zia ur Rehman, M.; Javed, M.R.; Imran, M.; Chatha, S.A.S.; Nazir, R. Zinc Oxide Nanoparticles Alter the Wheat Physiological Response and Reduce the Cadmium Uptake by Plants. Environmental Pollution 2018, 242, 1518–1526, doi:10.1016/j.envpol.2018.08.036. DOI: https://doi.org/10.1016/j.envpol.2018.08.036

Krishnan, A.; Swarnalal, A.; Das, D.; Krishnan, M.; Saji, V.S.; Shibli, S.M.A. A Review on Transition Metal Oxides Based Photocatalysts for Degradation of Synthetic Organic Pollutants. Journal of Environmental Sciences 2024, 139, 389–417, doi:10.1016/j.jes.2023.02.051. DOI: https://doi.org/10.1016/j.jes.2023.02.051

Kisimba, K.; Krishnan, A.; Faya, M.; Byanga, K.; Kasumbwe, K.; Vijayakumar, K.; Prasad, R. Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles. J. Renew. Mater. 2023, 11, 2575–2591, doi:10.32604/jrm.2023.026159. DOI: https://doi.org/10.32604/jrm.2023.026159

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Published

2026-02-09

How to Cite

L. Mustafa, L., & K. Qasim, A. (2026). Green Synthesis of Metal Oxide Nanoparticles Using Plant Extracts with Emphasis on Vigna unguiculata (Cowpea): A Review. Dasinya Journal for Engineering and Informatics, 2(1). https://doi.org/10.65542/djei.v2i1.24

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